Tag: covishield

Time to abandon mRNA vaccine boosters?

Aside Dr Amit Thadhani4 Comments

mRNA vaccines are a great technological advance, but the medium-term results are proving disappointing. When a virus enters a human body, it faces a formidable line of defence, known as the immune system. Various weapons are thrown at the virus, such as antibodies that bind with the virus and destroy it, and cells that can […]

Booster dose for COVID vaccination: Needed or Not?

Aside Dr Amit Thadhani3 Comments

It is well known that two doses of COVID vaccination – whether it is Pfizer, Moderna, AstraZeneca/Covishield or Covaxin – offer excellent protection against moderate and severe COVID (95-97%) but not against mild and asymptomatic disease (28%). Booster doses have been a matter of speculation since the early days of COVID vaccination when it was […]

AstraZeneca – Covishield delayed booster: Classic case of using bad science in the Lancet to make politically convenient decisions

Aside Dr Amit Thadhani2 Comments

“Modelling analyses showed an increase in vaccine efficacy after two standard doses from 55·1% (95% CI 33·0 to 69·9) with an interval of less than 6 weeks to 81·3% (60·3 to 91·2) with an interval of at least 12 weeks. A single standard dose had an efficacy against symptomatic COVID-19 in the first 90 days […]